INT299783
From wiki-pain
(Difference between revisions)
|
|
| Line 166: |
Line 166: |
| | |- | | |- |
| | | | |
| − | |}| | + | |} |
| | + | | |
| | | | | | |
| | {| cellspacing=1 cellpadding=5 align=center | | {| cellspacing=1 cellpadding=5 align=center |
Revision as of 13:03, 12 September 2012
| Context
|
Info
|
| Confidence
|
0.3651028500
|
| First Reported
|
2005
|
| Last Reported
|
2010
|
| Negated
|
0
|
| Speculated
|
0
|
| Reported most in
|
NULL
|
| Documents
|
7
|
| Total Number
|
8
|
|
|
|
Sentences Mentioned In
| Key:
|
Protein
|
Event
|
Anatomy
|
Negation
|
Speculation
|
Pain term
|
| In addition to the CD80/86-CD28 interaction, co-stimulation of T cell responses occurs through the CD40-CD154 interaction between APCs and T cells.
|
| CD28 Binding (interaction) of CD80 in T cell
|
|
| 1)
|
Confidence
|
0.140812717444618
|
Published
|
2010
|
Journal
|
N/A
|
Section
|
N/A
|
Doc Link
|
PMC2875641
|
|
| In addition to the CD80/86-CD28 interaction, co-stimulation of T cell responses occurs through the CD40-CD154 interaction between APCs and T cells.
|
| CD28 Binding (interaction) of CD80 in T cell
|
|
| 2)
|
Confidence
|
0.140812717444618
|
Published
|
2010
|
Journal
|
N/A
|
Section
|
N/A
|
Doc Link
|
PMC2875641
|
|
| These observations suggest that CD28CD80/86 interactions are important in the initiation of the arthritis.
|
| CD28 Binding (interactions) of CD80
|
|
| 3)
|
Confidence
|
0.083477425726812
|
Published
|
2005
|
Journal
|
N/A
|
Section
|
N/A
|
Doc Link
|
PMC2833980
|
|
| These observations suggest that CD28CD80/86 interactions are important in the initiation of the arthritis.
|
| CD28 Binding (interactions) of CD80
|
|
| 4)
|
Confidence
|
0.083477425726812
|
Published
|
2005
|
Journal
|
N/A
|
Section
|
N/A
|
Doc Link
|
PMC2833980
|
|
| The regulatory effects of interrupting CD28 interactions with CD80/86 have been harnessed in recombinant molecules (CTLA4immunoglobulin [Ig]) that combine the extracellular domain of human CTLA4 with a portion of the Fc domain of IgG1 [10].
|
| CD28 Binding (interactions) of CD80
|
|
| 5)
|
Confidence
|
0.083477425726812
|
Published
|
2005
|
Journal
|
N/A
|
Section
|
N/A
|
Doc Link
|
PMC2833980
|
|
| CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
|
| CD28 Binding (binds) of CD80 in dendritic cells
|
|
| 6)
|
Confidence
|
0.083477425726812
|
Published
|
2005
|
Journal
|
N/A
|
Section
|
N/A
|
Doc Link
|
PMC2833980
|
|
| CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
|
| CD28 Binding (binds) of CD80 in macrophages
|
|
| 7)
|
Confidence
|
0.0283823247471161
|
Published
|
2005
|
Journal
|
N/A
|
Section
|
N/A
|
Doc Link
|
PMC2833980
|
|
| CD28 is present on most T cells and it binds to both CD80 (B7-1) and CD86 (B7-2), which are present on antigen-presenting cells, including dendritic cells, B cells, and macrophages.
|
| CD28 Binding (binds) of CD80 in B cells
|
|
| 8)
|
Confidence
|
0.0283823247471161
|
Published
|
2005
|
Journal
|
N/A
|
Section
|
N/A
|
Doc Link
|
PMC2833980
|
|
This test has worked.
