INT300288

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Context Info
Confidence 0.57
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.91
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Foxo3) nucleus (Foxo3) embryo development (Foxo3)
DNA binding (Foxo3) transcription factor binding (Foxo3) response to stress (Foxo3)
Foxo3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 14 93.40 High High
anesthesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Perioperative pain 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 8 98.56 Very High Very High Very High
Diabetes Mellitus 55 93.88 High High
Fibrosis 12 93.40 High High
Apoptosis 40 92.36 High High
Hypertrophy 14 91.92 High High
Sprains And Strains 3 87.28 High High
Coronary Heart Disease 10 80.84 Quite High
Myocardial Infarction 78 77.92 Quite High
Acute Decompensated Heart Failure (ADHF) 1 42.84 Quite Low
Ventricular Remodeling 1 30.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Key changes in the posttranslational modification and expression of stress response proteins were decreased Akt phosphorylation and a concomitant increase in FOXO3a activation.
Positive_regulation (increase) of Positive_regulation (activation) of FOXO3a associated with stress
1) Confidence 0.57 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2835668 Disease Relevance 1.91 Pain Relevance 0.09

General Comments

This test has worked.

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