INT301203

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Slfn4 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 14 85.12 High High
Breast Cancer 4 82.80 Quite High
Myeloid Leukemia 112 82.32 Quite High
Myelodysplastic Syndromes 2 77.88 Quite High
Myeloproliferative Disorder 44 76.68 Quite High
Leukemia 34 76.48 Quite High
Hematologic Neoplasms 4 74.84 Quite High
Disease 16 64.44 Quite High
Targeted Disruption 4 63.20 Quite High
Starvation 2 62.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our gene array expression studies revealed decreased expression of HBP1, Slfn4, Dnmt3L, and Cdc42ep2 in miR-29a mutant cells compared with WT controls, and HBP1 appeared to be one of the authentic targets of miR-29a.
Gene_expression (expression) of Slfn4
1) Confidence 0.39 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.75 Pain Relevance 0
Consistent with being physiological targets of miR-29a, decreased expression was confirmed for a subset of the genes by Western blot or semiquantitative PCR analyses, including Cdc42ep2, Slfn4, and HBP1 (Fig. 6, b and c, and Fig.
Gene_expression (expression) of Slfn4
2) Confidence 0.30 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.55 Pain Relevance 0

General Comments

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