INT301401

Context Info Confidence 0.23 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.54 Pain Relevance 0

extracellular space (Enpp1, Enpp2) generation of precursor metabolites and energy (Enpp1) extracellular region (Enpp2) plasma membrane (Enpp1)

Enpp1 (Mus musculus) Enpp2 (Mus musculus)

Pain Link Frequency Relevance Heat Neuropathic pain 1 7.80 rheumatoid arthritis 1 6.88 Potency 2 5.00 palliative 1 5.00 cytokine 1 5.00 Inflammation 1 5.00 Pain 1 5.00 Immobilon 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Breast Cancer 46 81.28 Metastasis 57 80.08 Advanced Or Metastatic Breast Cancer 1 63.84 Osteoporosis 4 59.16 Cancer 68 50.00 Targeted Disruption 4 41.80 Hepatocellular Cancer 1 39.16 Thyroid Neoplasm 1 37.92 Skin Cancer 2 35.72 Lung Cancer 2 34.88

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Therefore, as a control cell line we transfected MDA-B02 cells with an expression vector coding for mouse NPP1, which acts as a nucleotide phosphodiesterase but that lacks for the lysoPLD activity.

NPP1 Binding (lacks) of lysoPLD

1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2840030 Disease Relevance 0.54 Pain Relevance 0

General Comments

This test has worked.