INT301559

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0.80
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp4f18) endoplasmic reticulum (Cyp4f18)
Anatomy Link Frequency
ventricle 1
liver 1
Cyp4f18 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 3 71.64 Quite High
Inflammation 22 71.60 Quite High
Inflammatory response 1 54.08 Quite High
alcohol 5 38.32 Quite Low
fibrosis 11 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
Calcium channel 6 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 27 88.48 High High
Cardiovascular Disease 9 85.20 High High
Reperfusion Injury 3 72.40 Quite High
Cv Unclassified Under Development 3 71.64 Quite High
INFLAMMATION 21 71.60 Quite High
Hypoxia 6 61.20 Quite High
Increased Venous Pressure Under Development 7 59.92 Quite High
Starvation 8 42.12 Quite Low
Coronary Heart Disease 3 21.28 Low Low
Apoptosis 9 19.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, CYP4F3B splice variant of the CYP4F3 gene expressed in liver and has a similar affinity as CYP4F2 for LTB4 [122].
Transcription (variant) of CYP4F3B in liver
1) Confidence 0.04 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.19 Pain Relevance 0.09
In this light, the objectives of our study were: 1) to determine the relative levels of CYP450 mRNAs (CYP1, CYP2, CYP3 and CYP4 families) in a large cohort (n?
Spec (determine) Transcription (levels) of CYP450
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001885 Disease Relevance 0.36 Pain Relevance 0.04
Thum and Borlak's group suggest that CYP450 mRNAs are predominantly expressed in the right ventricle.[10] In contrast, our results clearly show the presence of CYP450 mRNAs in the left ventricles.
Transcription (expressed) of CYP450 in ventricle
3) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001885 Disease Relevance 0.20 Pain Relevance 0
This study determined cardiac mRNA levels of various CYP450 isozymes involved in drug metabolism and demonstrated the prevalent expression of CYP2J2 mRNA.
Spec (determined) Transcription (levels) of CYP450
4) Confidence 0.01 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC3001885 Disease Relevance 0.06 Pain Relevance 0

General Comments

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