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Context Info
Confidence 0.48
First Reported 1985
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr2b) cytoplasm (Htr2b) signal transducer activity (Htr2b)
Anatomy Link Frequency
smooth muscle cells 2
Htr2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 4 96.36 Very High Very High Very High
antagonist 5 94.16 High High
Clonidine 1 90.32 High High
agonist 6 86.28 High High
Serotonin 3 75.00 Quite High
withdrawal 1 71.04 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, the 5-HT2 receptor, but not the transporter, is responsible for initiating the acute effects (e.g., calcium transients) of 5-HT in cultured rat pulmonary vascular smooth muscle cells and fluoxetine (1 microM) may have 5-HT2-receptor antagonist properties.
Gene_expression (responsible) of 5-HT2 in smooth muscle cells associated with antagonist and fluoxetine
1) Confidence 0.48 Published 1994 Journal Am. J. Physiol. Section Abstract Doc Link 8141313 Disease Relevance 0 Pain Relevance 0.53
Methoxamine and B-HT920 produced depolarization of similar magnitude of the membrane of the vascular smooth muscle cells.
Gene_expression (produced) of B-HT920 in smooth muscle cells
2) Confidence 0.01 Published 1985 Journal Clin. Sci. Section Abstract Doc Link 2857620 Disease Relevance 0 Pain Relevance 0.40

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