INT301600

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Context Info
Confidence 0.47
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP4F2) endoplasmic reticulum (CYP4F2)
Anatomy Link Frequency
liver 1
CYP4F2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 70.40 Quite High
chemokine 4 69.28 Quite High
Inflammation 16 23.96 Low Low
fibrosis 11 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Liver Disease 18 99.40 Very High Very High Very High
Obesity 11 90.04 High High
Fatty Liver 63 86.88 High High
Celiac Disease 2 38.56 Quite Low
Disease 13 26.40 Quite Low
INFLAMMATION 15 23.96 Low Low
Injury 8 18.60 Low Low
Biliary Liver Cirrhosis 2 16.00 Low Low
Cholangitis 1 12.16 Low Low
Autoimmune Hepatitis 1 11.12 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, the activation of the CYP4F2 gene in fatty liver diseases may decrease the formation of oleic acid and storage of TAG in the liver, and also play a vital role in preventing recruitment of immune cells to the liver during steatohepatitis by metabolism of the proinflammatory leukotrienes.
Positive_regulation (activation) of CYP4F2 in liver associated with liver disease
1) Confidence 0.47 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.28 Pain Relevance 0.13

General Comments

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