INT302153

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTGER2) signal transducer activity (PTGER2)
Anatomy Link Frequency
A549 2
PTGER2 (Homo sapiens)
AREG (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 5 57.76 Quite High
COX-2 inhibitor 52 5.00 Very Low Very Low Very Low
Inflammation 26 5.00 Very Low Very Low Very Low
cINOD 17 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fever 41 100.00 Very High Very High Very High
Adenocarcinoma 5 96.08 Very High Very High Very High
Lung Cancer 7 86.68 High High
Cancer 126 82.40 Quite High
Metastasis 5 75.28 Quite High
Apoptosis 151 51.80 Quite High
Death 27 50.00 Quite Low
Granuloma 1 44.80 Quite Low
Sarcoma 1 38.12 Quite Low
INFLAMMATION 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this case, PGE2 mediates its effect by the release of amphiregulin, the most abundant ligand in A549 cells [59].
PGE2 Positive_regulation (mediates) of Localization (release) of amphiregulin in A549 associated with fever
1) Confidence 0.06 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 1.10 Pain Relevance 0.03

General Comments

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