INT302157

Context Info Confidence 0.09 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.26 Pain Relevance 0.08

cytoplasm (MRPL28, CDKN2A) nucleoplasm (CDKN2A) mitochondrion (MRPL28) structural constituent of ribosome (MRPL28) ribosome (MRPL28) DNA binding (CDKN2A)

MRPL28 (Homo sapiens) CDKN2A (Homo sapiens)

Pain Link Frequency Relevance Heat COX-2 inhibitor 52 59.60 antagonist 5 52.76 Inflammation 26 5.00 cINOD 17 5.00 cytokine 11 5.00 aspirin 4 5.00 Paracetamol 3 5.00 Spinal cord 2 5.00 withdrawal 2 5.00 Pain 2 5.00

Disease Link Frequency Relevance Heat Cancer 126 95.28 Retinoblastoma 2 84.96 Death 27 50.00 Colon Cancer 23 27.96 Apoptosis 151 5.00 Fever 41 5.00 INFLAMMATION 28 5.00 Leukemia 9 5.00 Prostate Cancer 8 5.00 Lung Cancer 7 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The INK4 family (p16, p15, p18, and p19) and the Cip/Kip family (p21, p27, and p57) [54, 80, 81] are key regulators of G1/S transition.

p15 Regulation (regulators) of INK4

1) Confidence 0.09 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 0.26 Pain Relevance 0.08

General Comments

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