INT304055

Context Info Confidence 0.14 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.57 Pain Relevance 0

nucleus (TWIST1) DNA binding (TWIST1) transcription factor binding (TWIST1)

TWIST1 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 1 5.00 pain pelvic 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Carcinosarcoma 29 71.36 Cancer 85 69.12 Carcinoma 61 65.68 Sarcoma 23 64.48 Metastasis 4 45.12 Microsatellite Instability 47 35.40 Adenosarcoma 3 34.00 Malignant Neoplastic Disease 18 25.44 Leiomyosarcoma 9 15.60 Uterine Fibroids 5 14.12

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A number of specific transcription factors, including Snail, Slug, SIP-1, and Twist, contribute to induction of epithelial mesenchymal transition, acting as transcriptional repressors of the E-cadherin gene.

Transcription (transcription) of Twist

1) Confidence 0.14 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 0.57 Pain Relevance 0

General Comments

This test has worked.