INT304071

Context Info Confidence 0.28 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.11 Pain Relevance 0

nuclear chromosome (MSH6) ATPase activity (MSH6) nucleus (MSH6)

Anatomy Link Frequency MLH1 1 MSH6 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 1 7.68 pain pelvic 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Microsatellite Instability 47 91.68 Endometroid Carcinoma 21 76.36 Carcinoma 61 67.08 Endometrial Cancer 153 66.64 Cancer 85 57.76 Metaplasia 3 37.12 Endometrial Hyperplasia 4 36.12 Hyperplasia 18 30.00 Metastasis 4 14.12 Endometrial Stromal Sarcoma 39 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Mammalian mismatch repair (MMR) genes encode for nine proteins (MLH1, MLH3, PMS1, PMS2, MSH2, MSH3, MSH4, MSH5, and MSH6) that interact with each other to form complexes and heterodimers that mediate distinct functions in MMR-related system.

MSH6 Binding (interact) of in MLH1

1) Confidence 0.28 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 1.11 Pain Relevance 0

General Comments

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