INT305406

Context Info Confidence 0.16 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.86

Golgi apparatus (CAV3, ST8SIA2) cell differentiation (CAV3) protein modification process (ST8SIA2) carbohydrate metabolic process (ST8SIA2) cytoplasm (CAV3)

CAV3 (Homo sapiens) ST8SIA2 (Homo sapiens)

Pain Link Frequency Relevance Heat tetrodotoxin 84 100.00 addiction 4 63.92 local anesthetic 1 59.84 Nav1.1 5 5.00 Nav1.2 3 5.00 Nav1.6 1 5.00 conotoxin 1 5.00 Glutamate 1 5.00

Disease Link Frequency Relevance Heat Fatigue 1 5.00 Paralysis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition there is an unconfirmed report that one isoform group of the T type Ca channel (Cav3) binds TTX and STX and is blocked with low toxin affinity [17]. 2.

Cav3 Binding (binds) of STX associated with tetrodotoxin

1) Confidence 0.16 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2852835 Disease Relevance 0 Pain Relevance 0.86

General Comments

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