INT305883

Context Info Confidence 0.04 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.11 Pain Relevance 0.04

mitochondrion (Pcx) Golgi apparatus (Tjp1) plasma membrane (Tjp1) nucleus (Tjp1) cytoplasm (Tjp1)

Pcx (Mus musculus) Tjp1 (Mus musculus)

Pain Link Frequency Relevance Heat agonist 1 89.56 Inflammatory mediators 1 48.84 Central nervous system 3 29.24 Neurobehavioral 1 12.64 imagery 2 5.00 metalloproteinase 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Cancer 21 61.08 Breast Cancer 1 51.44 Metastasis 25 50.00 Adhesions 2 49.64 INFLAMMATION 1 48.44 Stress 3 47.20 Central Nervous System Disease 2 29.56 Brain Tumor 6 23.36 Dementia 1 22.64 Motor Neuron Diseases 1 21.36

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Exposure to PCB118 and PCB153 modulated expressional levels of claudin-5 and ZO-1, whereas PCB126 appeared to primarily influence the coassociation of occludin and ZO-1.

PCB126 Negative_regulation (influence) of ZO-1 Spec (appeared) Binding (coassociation) of

1) Confidence 0.04 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854723 Disease Relevance 0.11 Pain Relevance 0.04

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