INT306261

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (AKT2, FOXO1) cytoplasm (AKT2, FOXO1) cytosol (AKT2, FOXO1)
nucleus (AKT2, FOXO1) transport (AKT2) mitochondrion (AKT2)
AKT2 (Homo sapiens)
FOXO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 106 96.68 Very High Very High Very High
Inflammation 19 94.12 High High
metalloproteinase 4 36.44 Quite Low
cytokine 17 35.40 Quite Low
dexamethasone 7 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Etanercept 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 103 96.68 Very High Very High Very High
INFLAMMATION 22 94.12 High High
Reprotox - General 1 2 76.24 Quite High
Arthritis 5 40.60 Quite Low
Death 3 33.36 Quite Low
Apoptosis 12 32.92 Quite Low
Disease 12 5.00 Very Low Very Low Very Low
Cancer 11 5.00 Very Low Very Low Very Low
Leukemia 5 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is connected to AKT2 and AKT2 inhibits the phosphorylation of FOXO1.
AKT2 Negative_regulation (inhibits) of Phosphorylation (phosphorylation) of FOXO1
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.41 Pain Relevance 0.17

General Comments

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