INT306465

Context Info Confidence 0.34 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.30 Pain Relevance 0.08

peptidase activity (MASP2) extracellular region (MASP2)

MASP2 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 12 90.56 cytokine 5 5.00 chemokine 1 5.00 Pain 1 5.00 Antihistamine 1 5.00

Disease Link Frequency Relevance Heat Skin Infection 9 95.20 Staphylococcus Infection 3 93.84 INFLAMMATION 12 90.56 Disease 17 88.40 Dermatological Disease 9 87.00 Syndrome 1 85.12 Ulcers 1 83.44 Recurrence 2 75.84 Infection 13 74.72 Apoptosis 6 73.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Genotype analysis revealed specific point mutations in the MBL2 promoter in all 6 patients and a variant MASP-2 gene in one patient.

Negative_regulation (gene) of MASP-2

1) Confidence 0.34 Published 2010 Journal Clin Mol Allergy Section Abstract Doc Link PMC2856528 Disease Relevance 1.30 Pain Relevance 0.08

General Comments

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