INT307476

Context Info Confidence 0.09 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0

cytosol (Gsk3a) signal transduction (Gsk3a) carbohydrate metabolic process (Gsk3a)

Gsk3a (Rattus norvegicus)

Pain Link Frequency Relevance Heat agonist 7 5.00 Glutamate 5 5.00 antagonist 4 5.00 nMDA receptor 3 5.00 withdrawal 2 5.00 addiction 2 5.00 Spinal cord 1 5.00 Inflammation 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 13 55.60 Death 6 5.00 Pain 1 5.00 Neurodegenerative Disease 1 5.00 INFLAMMATION 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition, MAPKs were also involved in the survival signalling mechanism triggered by BDNF (Fig. 6).Fig. 5Effect of PKC and MAPK inhibition on GSK3 phosphorylation levels under conditions of PI3K inhibition.

Negative_regulation (inhibition) of Gene_expression (levels) of GSK3

1) Confidence 0.09 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2858808 Disease Relevance 0.06 Pain Relevance 0

General Comments

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