INT308649

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ppp1r13b, Iars) cytoplasm (Ppp1r13b, Iars) plasma membrane (Ppp1r13b)
translation (Iars) ligase activity (Iars)
Anatomy Link Frequency
SH2 1
Ppp1r13b (Mus musculus)
Iars (Mus musculus)
Pain Link Frequency Relevance Heat
Pyramidal cell 2 84.80 Quite High
Hippocampus 10 29.40 Quite Low
cerebral cortex 3 28.60 Quite Low
Central nervous system 14 10.64 Low Low
Kinase C 18 5.00 Very Low Very Low Very Low
Inflammation 18 5.00 Very Low Very Low Very Low
cytokine 13 5.00 Very Low Very Low Very Low
diabetic neuropathy 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 50 77.64 Quite High
Disease 100 76.28 Quite High
Dementia 15 50.00 Quite Low
Cognitive Disorder 8 39.60 Quite Low
Congenital Anomalies 6 5.44 Low Low
INFLAMMATION 20 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 20 5.00 Very Low Very Low Very Low
Cardiovascular Disease 19 5.00 Very Low Very Low Very Low
Vascular Dementia 17 5.00 Very Low Very Low Very Low
Coronary Artery Disease 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tyrosine-phosphorylated IRS associates with the two SH2 domains of the regulatory subunit p85, which in turn binds the catalytic subunit p110.
p85 Binding (associates) of IRS in SH2
1) Confidence 0.01 Published 2010 Journal The Open Biochemistry Journal Section Body Doc Link PMC2864432 Disease Relevance 0.29 Pain Relevance 0.04

General Comments

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