INT309350

Context Info Confidence 0.14 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0.08

nucleus (Lhx5) DNA binding (Lhx5) cell-cell signaling (Lhx5)

Anatomy Link Frequency neural 1 Lhx5 (Mus musculus)

Pain Link Frequency Relevance Heat Spinal cord 48 97.88 GABAergic 17 69.08 gABA 28 30.00 Dorsal horn 5 21.76 Dorsal horn neuron 1 8.40 Neurotransmitter 30 5.00 midbrain 8 5.00 Hippocampus 7 5.00 medulla 6 5.00 Thalamus 6 5.00

Disease Link Frequency Relevance Heat Lung Cancer 1 68.56 Ganglion Cysts 10 42.40 Pain 3 5.00 Targeted Disruption 2 5.00 Nociception 2 5.00 Sleep Disorders 1 5.00 Death 1 5.00 Spasticity 1 5.00 Depression 1 5.00 Muscle Hypertonia 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Knockdown of Lhx1 and Lhx5 results in decreased expression of VIAAT, although they do not appear to be obligatory determinant of inhibitory neural phenotypes and appear to play no direct role in determining GlyT2 expression (Pillai et al., 2007).

Negative_regulation (Knockdown) of Lhx5 in neural

1) Confidence 0.14 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2866564 Disease Relevance 0.07 Pain Relevance 0.08

General Comments

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