INT310010

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 16
Disease Relevance 2.95
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Slc30a4) transport (Slc30a4) cytoplasmic membrane-bounded vesicle (Slc30a4)
transmembrane transport (Slc30a4)
Anatomy Link Frequency
villus 4
MDCK 4
epithelium 2
intestinal villi 1
Slc30a4 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 32 93.72 High High
ketamine 16 44.52 Quite Low
anesthesia 16 41.80 Quite Low
agonist 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 368 99.92 Very High Very High Very High
Infection 752 97.84 Very High Very High Very High
Bacterial Respiratory Disease 16 89.48 High High
Sarcoma 16 84.44 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 16 83.72 Quite High
Food Poisoning 16 80.56 Quite High
Disease 64 63.24 Quite High
Enteritis 16 60.96 Quite High
Peripheral Arterial Disease 16 47.84 Quite Low
Adhesions 80 27.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lm were detected by incubation of samples with biotin-conjugated rabbit anti-L. monocytogenes, all antigens (YVS4207, Accurate Chemical & Scientific Corp., Westbury, NY; 1?
Gene_expression (detected) of Lm
1) Confidence 0.33 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0 Pain Relevance 0.04
We infected MDCK monolayers polarized on Transwell filters from the apical side with GFP-expressing wild type Lm (WT) or GFP-expressing inlB-mutant Lm (?
Gene_expression (expressing) of Lm in MDCK
2) Confidence 0.33 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0 Pain Relevance 0
We infected MDCK monolayers polarized on Transwell filters from the apical side with GFP-expressing wild type Lm (WT) or GFP-expressing inlB-mutant Lm (?
Gene_expression (expressing) of Lm in MDCK
3) Confidence 0.33 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0 Pain Relevance 0
We infected MDCK monolayers polarized on Transwell filters from the apical side with GFP-expressing wild type Lm (WT) or GFP-expressing inlB-mutant Lm (?
Gene_expression (expressing) of Lm in MDCK
4) Confidence 0.33 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0 Pain Relevance 0
Without InlB, Lm invasion is less efficient.
Gene_expression (invasion) of Lm
5) Confidence 0.33 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.24 Pain Relevance 0
We infected mice intragastrically with isogenic strains of Lm that express or lack InlB and that have a modified InlA capable of binding murine E-cadherin and found that Lm lacking InlB invade the same number of villi but have decreased numbers of bacteria within each infected villus tip.
Neg (lacking) Gene_expression (lacking) of Lm in villus associated with sprains and strains
6) Confidence 0.33 Published 2010 Journal PLoS Pathogens Section Abstract Doc Link PMC2869327 Disease Relevance 0.10 Pain Relevance 0.04
In contrast to Lm expressing wild type InlA, Lm expressing InlAm are pathogenic to mice by enteric inoculation [44].
Gene_expression (expressing) of Lm
7) Confidence 0.29 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.07 Pain Relevance 0
In contrast to Lm expressing wild type InlA, Lm expressing InlAm are pathogenic to mice by enteric inoculation [44].
Gene_expression (expressing) of Lm
8) Confidence 0.29 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.12 Pain Relevance 0
We also find that Lm invasion of a polarized epithelium through the MCJs requires functional dynamin even in the absence of InlB.
Gene_expression (invasion) of Lm in epithelium
9) Confidence 0.28 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.20 Pain Relevance 0
Other investigators have shown that Lm requires dynamin and other molecular components of clathrin-mediated endocytosis for efficient invasion of nonpolarized cells [55], [59], [73].
Gene_expression (requires) of Lm
10) Confidence 0.28 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.26 Pain Relevance 0
However, mice infected with WTm GFP have approximately twice the number of Lm per villus tip than mice infected with ?
Gene_expression (number) of Lm in villus
11) Confidence 0.28 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.64 Pain Relevance 0
We used 3D confocal microscopy analysis to characterize Lm invasion of villus tips within ?
Gene_expression (invasion) of Lm in villus
12) Confidence 0.28 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.58 Pain Relevance 0
We found that that ingestion of Lm does not result in generalized invasion of all intestinal villi.
Gene_expression (ingestion) of Lm in intestinal villi
13) Confidence 0.28 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.43 Pain Relevance 0
We infected mice intragastrically with Lm that express InlAm and GFP (WTm GFP) to study Lm invasion of the intestinal villous epithelium.
Gene_expression (express) of Lm in epithelium
14) Confidence 0.25 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0.21 Pain Relevance 0
We infected mice intragastrically with isogenic strains of Lm that express or lack InlB and that have a modified InlA capable of binding murine E-cadherin and found that Lm lacking InlB invade the same number of villi but have decreased numbers of bacteria within each infected villus tip.
Neg (lack) Gene_expression (express) of Lm in villus associated with sprains and strains
15) Confidence 0.25 Published 2010 Journal PLoS Pathogens Section Abstract Doc Link PMC2869327 Disease Relevance 0.10 Pain Relevance 0.05
We infected MDCK monolayers polarized on Transwell filters from the apical side with GFP-expressing wild type Lm (WT) or GFP-expressing inlB-mutant Lm (?
Gene_expression (expressing) of Lm in MDCK
16) Confidence 0.25 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2869327 Disease Relevance 0 Pain Relevance 0

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