INT311377

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.15 Pain Relevance 0

cytoplasm (Eef2, Pabpc1) mRNA binding (Pabpc1) mRNA processing (Pabpc1) RNA binding (Pabpc1) nucleus (Pabpc1) translation (Eef2)

Anatomy Link Frequency poly 1 Eef2 (Mus musculus) Pabpc1 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 2 5.00 Central nervous system 2 5.00 spastic colon 1 5.00 depression 1 5.00 Inflammation 1 5.00

Disease Link Frequency Relevance Heat Toxicity 16 79.44 Myotonic Dystrophy 22 50.00 Disease 13 50.00 Muscular Atrophy 4 11.52 Targeted Disruption 19 5.76 Myotonia 14 5.00 Congenital Anomalies 11 5.00 Cataract 7 5.00 Frailty 7 5.00 Aging 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Consistent with this hypothesis, a recent report has shown that ZNF9 interacts with the 5’ UTRs of TOP (terminal oligopyrimidine tract) mRNAs that encode proteins of translational apparatus: human ribosomal protein, RPS17, poly(A)-binding protein, PABP, and elongation factors, eEF1A and eEF2 [96].

eEF2 Binding (interacts) of PABP in poly

1) Confidence 0.01 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.15 Pain Relevance 0

General Comments

This test has worked.