INT311632

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Wnt1) extracellular space (Wnt1) extracellular region (Wnt1)
proteinaceous extracellular matrix (Wnt1) plasma membrane (Wnt1) cell-cell signaling (Wnt1)
Anatomy Link Frequency
embryos 1
Wnt1 (Mus musculus)
Pain Link Frequency Relevance Heat
midbrain 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
vagus nerve 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 27 100.00 Very High Very High Very High
Apoptosis 19 90.72 High High
Sprains And Strains 1 16.44 Low Low
Cleft Palate 8 5.00 Very Low Very Low Very Low
Congenital Anomalies 7 5.00 Very Low Very Low Very Low
Persistent Truncus Arteriosus 4 5.00 Very Low Very Low Very Low
Ventricular Heart Septal Defects 4 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Polydactyly 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To gain insight into the possible mechanisms that contribute to the craniofacial defects observed in Spry1;Wnt1-Cre embryos we crossed the conditional CAGGFP-Spry1 mice with R26R;Wnt1-Cre transgenic mice to generate Spry1;R26R;Wnt1-Cre mutant embryos.
Positive_regulation (generate) of Wnt1 in embryos associated with targeted disruption
1) Confidence 0.43 Published 2010 Journal BMC Dev Biol Section Body Doc Link PMC2874773 Disease Relevance 0.19 Pain Relevance 0

General Comments

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