INT312975

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

small molecule metabolic process (MSMO1) oxidoreductase activity (MSMO1) endoplasmic reticulum (MSMO1) plasma membrane (MSMO1)

Anatomy Link Frequency respiratory 1 MSMO1 (Homo sapiens)

Pain Link Frequency Relevance Heat Pain 6 5.00 peripheral neuropathy 2 5.00 halothane 2 5.00 agonist 1 5.00 Glutamate 1 5.00 antiepileptic Drug 1 5.00 backache 1 5.00 positron emission tomography 1 5.00

Disease Link Frequency Relevance Heat Disease 31 5.00 Muscle Disease 23 5.00 Coronary Heart Disease 17 5.00 Glycogen Storage Disease 10 5.00 Hypoglycemia 10 5.00 Muscle Weakness 10 5.00 Myoglobinuria 8 5.00 Malignant Hyperthermia 8 5.00 Congenital Anomalies 8 5.00 Heart Rate Under Development 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

NO can inhibit mitochondrial cytochrome c-oxidase (complex IV) of the respiratory chain by reversibly competing with oxygen for the binding site.

Negative_regulation (inhibit) of c-oxidase in respiratory

1) Confidence 0.01 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2877206 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.