INT313633

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.23

molecular_function (Gm318) cellular_component (Gm318) biological_process (Gm318)

Anatomy Link Frequency neurons 1 Gm318 (Mus musculus) Tg(CAG-EGFP)D4Nagy (Mus musculus)

Pain Link Frequency Relevance Heat nMDA receptor 79 92.24 antagonist 20 34.48 Dorsal horn 13 20.56 GABAergic 14 5.00 Spinal cord 8 5.00 Glutamate 7 5.00 projection neuron 6 5.00 Pain 5 5.00 agonist 5 5.00 allodynia 4 5.00

Disease Link Frequency Relevance Heat Pain 5 5.00 Neuropathic Pain 5 5.00 Targeted Disruption 3 5.00 Nervous System Injury 3 5.00 Disseminated Intravascular Coagulation 3 5.00 Death 2 5.00 INFLAMMATION 2 5.00 Apoptosis 1 5.00 Drug Induced Neurotoxicity 1 5.00 Depression 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

To confirm this speculation, we investigated the effect of EAB318 and UBP 141 on the conductance ratio and VMIC of EGFP- neurons.

EAB318 Spec (investigated) Regulation (effect) of EGFP in neurons

1) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC2879240 Disease Relevance 0 Pain Relevance 0.23

General Comments

This test has worked.