INT314063

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Peo1) helicase activity (Peo1)
Anatomy Link Frequency
macrophage 1
Peo1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 56 88.24 High High
agonist 2 86.40 High High
cytokine 22 78.60 Quite High
Inflammatory mediators 2 51.36 Quite High
Crohn's disease 8 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Piles 4 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 54 88.24 High High
Colitis 38 80.64 Quite High
Inflammatory Bowel Disease 76 77.92 Quite High
Disease 30 77.40 Quite High
Hyperplasia 2 43.40 Quite Low
Body Weight 10 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low
Hemorrhage 10 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Diarrhoea 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subsequently, we performed a gene array analysis (Table 5) using the same in vitro macrophage based system to elucidate additional immune signaling genes that could be potential targets of PEO activity.
Regulation (targets) of PEO in macrophage
1) Confidence 0.22 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.34 Pain Relevance 0.28
Therefore, we wanted to study the effects of PEO on activated (phosphorylated at Tyr701) STAT1 (pSTAT1).
Regulation (effects) of PEO
2) Confidence 0.19 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.30 Pain Relevance 0.04

General Comments

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