INT314077

Context Info Confidence 0.31 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.33 Pain Relevance 0.03

mitochondrion (Peo1) nucleolus (Stat1) nucleus (Stat1) helicase activity (Peo1) enzyme binding (Stat1) DNA binding (Stat1)

Peo1 (Mus musculus) Stat1 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 11 64.32 Inflammation 28 50.00 chemokine 3 40.48 Crohn's disease 4 5.00 Piles 2 5.00 aspirin 1 5.00 cINOD 1 5.00 Bioavailability 1 5.00 Inflammatory mediators 1 5.00 agonist 1 5.00

Disease Link Frequency Relevance Heat Inflammatory Bowel Disease 38 89.28 Colitis 19 83.36 Disease 15 82.72 INFLAMMATION 27 50.00 Body Weight 5 5.00 Cancer 5 5.00 Hemorrhage 5 5.00 Toxicity 2 5.00 Diarrhoea 2 5.00 Anorectal Disorders 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We have initiated a detailed investigation into the molecular mechanism of suppression of STAT1 activation by PEO that will be described elsewhere in the future.

PEO Negative_regulation (suppression) of Positive_regulation (activation) of STAT1

1) Confidence 0.31 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.33 Pain Relevance 0.03

General Comments

This test has worked.