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Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.09
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk14, Trpv1) mitochondrion (Mapk14) cell morphogenesis (Mapk14)
lipid metabolic process (Trpv1) response to stress (Mapk14) cytoplasm (Mapk14)
Mapk14 (Mus musculus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 45 99.78 Very High Very High Very High
allodynia 39 96.32 Very High Very High Very High
Cold hyperalgesia 1 95.92 Very High Very High Very High
Pain 17 84.12 Quite High
Spinal cord 6 83.48 Quite High
Trk A 11 80.48 Quite High
IPN 2 65.16 Quite High
Peripheral nervous system 1 61.48 Quite High
central pain 1 59.52 Quite High
Neuropathic pain 4 57.76 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 48 96.32 Very High Very High Very High
Hyperalgesia 7 95.72 Very High Very High Very High
Pain 15 84.12 Quite High
Diabetes Mellitus 44 75.80 Quite High
Nervous System Injury 3 66.24 Quite High
Inflammatory Pain 2 65.16 Quite High
Syndrome 1 59.92 Quite High
Osteoarthritis 1 48.64 Quite Low
INFLAMMATION 23 46.84 Quite Low
Hyperglycemia 3 41.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been proposed that NGF-activated p38 could increase the expression of transient receptor potential vallinoid (TRPV) 1 receptor [10] and transient receptor potential subfamily A 1 receptor [30] to mediate thermal and cold hyperalgesia respectively.
p38 Positive_regulation (increase) of Gene_expression (expression) of TRPV associated with hyperalgesia, cold hyperalgesia and nerve growth factor
1) Confidence 0.48 Published 2010 Journal Mol Pain Section Body Doc Link PMC2881061 Disease Relevance 1.09 Pain Relevance 1.24

General Comments

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