INT314266

Context Info Confidence 0.02 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.13 Pain Relevance 0.03

nucleoplasm (SUPT4H1) small molecule metabolic process (SPTLC1) endoplasmic reticulum (SPTLC1) biosynthetic process (SPTLC1) nucleus (SUPT4H1) transferase activity, transferring acyl groups (SPTLC1)

SUPT4H1 (Homo sapiens) SPTLC1 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 10 60.96 COX-2 inhibitor 3 23.08 Inflammatory mediators 2 5.00 melanocortin 1 receptor 1 5.00 Immobilon 1 5.00

Disease Link Frequency Relevance Heat Burns 5 66.48 INFLAMMATION 11 60.96 Stress 5 12.96 Erythema 9 5.00 Skin Cancer 4 5.00 Blister 2 5.00 Increased Venous Pressure Under Development 2 5.00 Dermatitis 1 5.00 Malignant Neoplastic Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Production of PGE2 in response to UVB is greater in SPT-1 EM than SPT-4 EM

SPT-4 Positive_regulation (greater) of SPT-1

1) Confidence 0.02 Published 2010 Journal Pigment Cell & Melanoma Research Section Body Doc Link PMC2881306 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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