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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.23
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 2
TRGC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 5 74.64 Quite High
abdominal pain 7 72.16 Quite High
Pain 10 60.12 Quite High
bradykinin 28 32.40 Quite Low
depression 1 31.12 Quite Low
Inflammation 3 5.00 Very Low Very Low Very Low
b2 receptor 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hereditary Angioedema 92 98.76 Very High Very High Very High
Emergencies 6 92.24 High High
Pressure And Volume Under Development 32 89.64 High High
Laryngeal Edema 4 79.92 Quite High
Exanthema 4 75.92 Quite High
Vomiting 6 75.68 Quite High
Headache 5 74.64 Quite High
Dizziness 1 74.24 Quite High
Asthenia 1 73.80 Quite High
Reprotox - General 1 2 72.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Prophylaxis for HAE attacks is available; either with attenuated androgens which increase hepatic production of endogenous C1 inhibitor, or by antifibrinolytics such as tranexamic acid or ??
Positive_regulation (increase) of Negative_regulation (inhibitor) of C1 associated with hereditary angioedema
1) Confidence 0.41 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2941790 Disease Relevance 1.38 Pain Relevance 0.06
The attenuated androgens, such as danazol, increase C1 inhibitor via the liver and carry the risk of long-term side effects[31].
Positive_regulation (increase) of Negative_regulation (inhibitor) of C1 in liver
2) Confidence 0.40 Published 2010 Journal BMC Blood Disord Section Body Doc Link PMC2881905 Disease Relevance 0.85 Pain Relevance 0.15

General Comments

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