INT316003

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.98 Pain Relevance 0.27

cytosol (As3mt) mitochondrion (As3mt) cytoplasm (As3mt)

Anatomy Link Frequency internal 1 body 1 As3mt (Rattus norvegicus)

Pain Link Frequency Relevance Heat Pain 16 94.56 Anterior cingulate cortex 8 93.60 insula 70 69.04 depression 76 63.36 primary afferent fibers 2 49.36 projection neuron 2 33.92 spinal dorsal horn 2 29.44 spinothalamic 2 25.28 Anterior cingulate 24 5.00 amygdala 18 5.00

Disease Link Frequency Relevance Heat Pain 12 94.56 Pruritus 2 89.20 Anxiety Disorder 134 87.80 Cognitive Disorder 24 85.88 Phobia 10 65.20 Depression 88 63.36 Traumatic Stress Disorders 4 12.36 Panic Disorder 4 6.88 Mental Disorders 6 5.00 Depressive Disorder 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Interoception comprises sensing the physiological condition of the body (Craig 2002), as well as the representation of the internal state (Craig 2009) within the context of ongoing activities, and is closely associated with motivated action to homeostatically regulate the internal state (Craig 2007).

Regulation (regulate) of state in internal

1) Confidence 0.00 Published 2010 Journal Brain Struct Funct Section Body Doc Link PMC2886901 Disease Relevance 0.74 Pain Relevance 0.09

Being aware of our internal state modulates approach and distancing behaviors which, in turn, help us maintain and regain homeostasis (i.e., regulation of internal body state).

Regulation (regulation) of state in body

2) Confidence 0.00 Published 2010 Journal Brain Struct Funct Section Body Doc Link PMC2886901 Disease Relevance 0.24 Pain Relevance 0.17

General Comments

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