INT316190

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Apc, Mapk1) nucleus (Apc, Mapk1) nucleoplasm (Mapk1)
mitochondrion (Mapk1) protein complex assembly (Apc) protein complex (Mapk1)
Anatomy Link Frequency
lung 2
Apc (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 3 98.52 Very High Very High Very High
Inflammation 18 85.12 High High
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Injury 39 100.00 Very High Very High Very High
INFLAMMATION 20 98.16 Very High Very High Very High
Urological Neuroanatomy 6 87.12 High High
Adult Respiratory Distress Syndrome 22 25.00 Low Low
Sepsis 9 25.00 Low Low
Hemorrhage 6 25.00 Low Low
Edema 7 5.00 Very Low Very Low Very Low
Injury 7 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Heart Rate Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mechanistically, we found a strong activation of ERK in lung tissues by VILI, which was prevented by APC, suggestive of pathogenetic involvement of the Mitogen-Activated Kinase pathway.
APC Negative_regulation (prevented) of Positive_regulation (activation) of ERK in lung associated with lung injury
1) Confidence 0.33 Published 2010 Journal Crit Care Section Abstract Doc Link PMC2887192 Disease Relevance 0.66 Pain Relevance 0.12

General Comments

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