INT316430

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.24
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cdkn1a) nucleus (Cdkn1a) cell cycle (Cdkn1a)
kinase activity (Cdkn1a) cytoplasm (Cdkn1a)
Cdkn1a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 81.60 Quite High
cytokine 22 5.00 Very Low Very Low Very Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 2 100.00 Very High Very High Very High
Skin Cancer 5 91.92 High High
Apoptosis 11 91.32 High High
Bladder Cancer 1 88.80 High High
Death 1 88.04 High High
Inflammatory Bowel Disease 6 82.16 Quite High
Colon Cancer 6 80.92 Quite High
Cancer 149 80.80 Quite High
Metastasis 4 54.40 Quite High
INFLAMMATION 47 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, Stat3 promotes proliferation primarily by stimulating transcription of cyclinB1, cdc2, c-myc and cyclinD1 [55,65,66], along with the induction of the immediate early genes c-jun and c-fos [67] and repression of the cell cycle inhibitor p21 [68].
Positive_regulation (induction) of Negative_regulation (repression) of p21 associated with repression
1) Confidence 0.19 Published 2010 Journal Cell Div Section Body Doc Link PMC2887830 Disease Relevance 1.24 Pain Relevance 0.04

General Comments

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