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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.55
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GH1, SST) extracellular region (GH1, SST) cell-cell signaling (SST)
Anatomy Link Frequency
hepatocytes 1
GH1 (Homo sapiens)
SST (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 36 100.00 Very High Very High Very High
Dopamine 44 91.44 High High
agonist 42 90.72 High High
metalloproteinase 1 76.88 Quite High
Bioavailability 1 65.40 Quite High
Onset of action 3 57.88 Quite High
withdrawal 8 5.00 Very Low Very Low Very Low
headache 5 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 78 99.68 Very High Very High Very High
Adenoma 18 89.44 High High
Acromegaly 36 81.16 Quite High
Pituitary Cancer 59 80.56 Quite High
Disease 59 62.20 Quite High
Hypopituitarism 3 58.92 Quite High
Prolactinoma 47 50.00 Quite Low
Thyroid Neoplasm 1 16.92 Low Low
Galactorrhea 10 5.00 Very Low Very Low Very Low
Recurrence 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently, it has been suggested that a sst ligand may also act peripherally on the GH/IGF-1 axis by binding to somatostatin receptors on peripheral organs, such as hepatocytes in the liver, to inhibit the secretion of IGF-1 [92].
GH Binding (binding) of somatostatin in hepatocytes associated with somatostatin
1) Confidence 0.03 Published 2010 Journal BMC Endocr Disord Section Body Doc Link PMC2887860 Disease Relevance 0.45 Pain Relevance 0.37
GH secretion is regulated through ligand binding of somatostatin to both sst2 and sst5, whereas SSA binds preferentially sst2 [26].
GH Binding (binding) of sst2 associated with somatostatin
2) Confidence 0.01 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC3017030 Disease Relevance 0.10 Pain Relevance 0.17

General Comments

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