INT317552

From wiki-pain
Revision as of 18:01, 20 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.07
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Car2) extracellular space (Car2) lyase activity (Car2)
cell cycle (Calm3) cytoplasm (Car2)
Anatomy Link Frequency
hippocampus 1
Calm3 (Mus musculus)
Car2 (Mus musculus)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 78 98.56 Very High Very High Very High
long-term potentiation 83 98.12 Very High Very High Very High
opioid receptor 84 96.08 Very High Very High Very High
Hippocampus 4 92.28 High High
Calcium channel 1 90.20 High High
nMDA receptor 12 88.16 High High
Glutamate 11 85.76 High High
Neurotransmitter 1 85.36 High High
Kinase C 39 70.24 Quite High
Pain 3 65.60 Quite High
Disease Link Frequency Relevance Heat
Pain 5 65.60 Quite High
Targeted Disruption 47 49.12 Quite Low
Urological Neuroanatomy 18 5.00 Very Low Very Low Very Low
Nociception 7 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Intractable Pain 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Herpes Simplex Virus Infection 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been well established that Ca2+ binds to calmodulin (CaM), which activates CaM target proteins, such as Ca2+/CaM-dependent protein kinases (PKC, CaMKII and CaMKIV), CaM-activated ACs (AC1 and 8), and the CaM-activated phosphatase calcineurin in the hippocampus [45,46].
CaM Binding (binds) of Ca2 in hippocampus associated with hippocampus
1) Confidence 0.06 Published 2010 Journal Mol Brain Section Body Doc Link PMC2949850 Disease Relevance 0.07 Pain Relevance 0.63
Ca2+-CaM then increases and activates CaMKII (13) that, in turn, acts on nNOS Ser847 to reduce Ca2+-CaM binding and NO production (14).
CaM Binding (binding) of Ca2
2) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890584 Disease Relevance 0 Pain Relevance 0.42

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox