INT317691

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Context Info
Confidence 0.69
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.42
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gabrq) plasma membrane (Gabrq)
Anatomy Link Frequency
hippocampus 1
Gabrq (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 48 96.72 Very High Very High Very High
antidepressant 30 90.24 High High
depression 45 80.32 Quite High
gABA 21 71.00 Quite High
monoamine 15 52.56 Quite High
agonist 27 35.28 Quite Low
amygdala 3 33.84 Quite Low
Catecholamine 3 14.76 Low Low
GABAergic 9 5.00 Very Low Very Low Very Low
fluoxetine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 141 98.98 Very High Very High Very High
Manic Depressive Disorder 6 98.60 Very High Very High Very High
Depression 57 80.32 Quite High
Affective Disorder 12 49.60 Quite Low
Autism 3 12.32 Low Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Depressive Disorder 6 5.00 Very Low Very Low Very Low
Anxiety Disorder 6 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gabrq was expressed at similar levels in all three strains, Gabre expression was not detected in the hippocampus of any of the strains, and Gpr50 expression was higher in B6 hippocampus than in NZB or R3 hippocampus.
Gene_expression (expressed) of Gabrq in hippocampus associated with hippocampus and sprains and strains
1) Confidence 0.69 Published 2010 Journal Mamm Genome Section Body Doc Link PMC2890984 Disease Relevance 0.51 Pain Relevance 0.34
RT-PCR was used to confirm this strain-specific expression difference and to measure the expression of several adjacent candidate genes, including Gabre, Gabrq, and Gpr50 (Fig. 4).
Gene_expression (expression) of Gabrq associated with sprains and strains
2) Confidence 0.60 Published 2010 Journal Mamm Genome Section Body Doc Link PMC2890984 Disease Relevance 0.50 Pain Relevance 0.33
We compared expression of the MMUX GABAA receptor subunit genes Gabra3, Gabre, and Gabrq, in hippocampal tissue from the NZB, B6, and R3 strains.
Gene_expression (expression) of Gabrq associated with sprains and strains
3) Confidence 0.47 Published 2010 Journal Mamm Genome Section Body Doc Link PMC2890984 Disease Relevance 0.41 Pain Relevance 0.11

General Comments

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