INT318142

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.12
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Car3) cytoplasm (Car3)
Anatomy Link Frequency
dentate gyrus 3
hippocampus 1
Car3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pyramidal cell 4 100.00 Very High Very High Very High
Hippocampus 56 98.88 Very High Very High Very High
depression 2 95.00 High High
gABA 40 80.88 Quite High
Central nervous system 2 64.72 Quite High
GABA receptor 2 55.56 Quite High
Glutamate 26 49.20 Quite Low
Calcium channel 2 43.84 Quite Low
nMDA receptor antagonist 4 26.80 Quite Low
nMDA receptor 24 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Injury 124 99.08 Very High Very High Very High
Depression 2 95.00 High High
Injury 132 93.56 High High
Drug Induced Neurotoxicity 4 47.76 Quite Low
Death 2 41.72 Quite Low
Apoptosis 22 5.00 Very Low Very Low Very Low
Convulsion 12 5.00 Very Low Very Low Very Low
Cognitive Disorder 10 5.00 Very Low Very Low Very Low
Hypoxia 8 5.00 Very Low Very Low Very Low
Epilepsy 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Contrary to the reduced inhibition in CA1 pyramidal cells [15] and CA3 to CA1 pathway [16] of the hippocampus, dentate gyrus granule cells [15] and the entorhinal cortex to dentate gyrus pathway demonstrated enhanced inhibition 2-15 days after fluid percussion TBI in rats [16].
Negative_regulation (reduced) of Negative_regulation (inhibition) of CA3 in dentate gyrus associated with pyramidal cell, hippocampus and brain injury
1) Confidence 0.16 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2893123 Disease Relevance 1.06 Pain Relevance 0.37
Contrary to the reduced inhibition in CA1 pyramidal cells [15] and CA3 to CA1 pathway [16] of the hippocampus, dentate gyrus granule cells [15] and the entorhinal cortex to dentate gyrus pathway demonstrated enhanced inhibition 2-15 days after fluid percussion TBI in rats [16].
Negative_regulation (reduced) of in hippocampus Negative_regulation (inhibition) of CA3 in dentate gyrus associated with pyramidal cell, hippocampus and brain injury
2) Confidence 0.05 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2893123 Disease Relevance 1.06 Pain Relevance 0.37

General Comments

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