INT318186

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (MUC5AC, VEGFA) extracellular space (VEGFA) growth (VEGFA)
proteinaceous extracellular matrix (VEGFA) cell adhesion (MUC5AC) cytoplasm (VEGFA)
MUC5AC (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 20 87.52 High High
Anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 28 100.00 Very High Very High Very High
Cancer 27 89.72 High High
Metastasis 14 78.08 Quite High
Rheumatoid Arthritis 1 35.84 Quite Low
Adhesions 11 5.00 Very Low Very Low Very Low
Pancreatic Ductal Carcinoma 5 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MUC5AC might contribute to the progression of pancreatic cancer by inducing adhesiveness and invasiveness in ECM via VEGF overexpression, indicating that MUC5AC may be a potentially target in the treatment of pancreatic cancer.


MUC5AC Positive_regulation (inducing) of Gene_expression (overexpression) of VEGF associated with pancreatic cancer
1) Confidence 0.22 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2893453 Disease Relevance 1.01 Pain Relevance 0.04

General Comments

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