INT318488

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (LTB4R, FPR2) signal transducer activity (LTB4R, FPR2) cell adhesion (FPR2)
LTB4R (Homo sapiens)
FPR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 31 99.44 Very High Very High Very High
Inflammation 28 95.40 Very High Very High Very High
dexamethasone 21 90.00 High High
cytokine 3 74.68 Quite High
agonist 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Occupational Lung Diseases 37 97.26 Very High Very High Very High
INFLAMMATION 28 95.40 Very High Very High Very High
Adhesions 3 92.96 High High
Asthma 101 70.16 Quite High
Rhinitis 3 8.00 Low Low
Hypersensitivity 1 6.96 Low Low
Nicotine Addiction 4 5.00 Very Low Very Low Very Low
Pulmonary Disease 2 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This differential response of AMs from severe asthmatics vis-a-vis LTB4 and LXA4 and the effect of corticosteroids (increased LTB4 in response to LPS and impaired CS suppression of the rise in LTB4 vs. little change in LXA4 in response to LPS and unimpaired CS suppression of LXA4 levels) may contribute to persistent airway neutrophilic inflammation since LXA4 can inhibit LTB4-induced chemotaxis, adhesion and transmigration[17].
LTB4 Neg (little) Regulation (change) of LXA4 associated with corticosteroid, inflammation, occupational lung diseases and adhesions
1) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC2894769 Disease Relevance 1.07 Pain Relevance 0.58

General Comments

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