INT318678

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Context Info
Confidence 0.53
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Atf4, Ddit3) DNA binding (Atf4, Ddit3) cytoplasm (Atf4, Ddit3)
aging (Ddit3) plasma membrane (Atf4) cytoskeleton (Atf4)
Anatomy Link Frequency
lung 2
Atf4 (Rattus norvegicus)
Ddit3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 29 98.16 Very High Very High Very High
Inflammation 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 26 98.16 Very High Very High Very High
Stress 31 95.92 Very High Very High Very High
Apoptosis 29 73.92 Quite High
Reperfusion Injury 2 39.20 Quite Low
Injury 4 25.28 Quite Low
Death 3 24.48 Low Low
Disease 1 16.08 Low Low
Diabetes Mellitus 2 14.48 Low Low
Neurodegenerative Disease 1 12.96 Low Low
Lung Injury 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Real-time PCR showed that XBP-1, ATF4, and CHOP mRNA levels in lung tissues of LIR rats drastically increased relative to those of control rats (M-W test, p = 0.027, p = 0.03, and p = 0.02, respectively).
ATF4 Positive_regulation (increased) of Gene_expression (levels) of CHOP mRNA in lung
1) Confidence 0.53 Published 2010 Journal Acta Orthopaedica Section Body Doc Link PMC2895349 Disease Relevance 0.77 Pain Relevance 0.23

General Comments

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