INT320783

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.98
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Flt4) nucleus (Flt4) kinase activity (Flt4)
cytoplasm (Flt4)
Anatomy Link Frequency
vasculature 1
dendritic cell 1
Flt4 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 1 92.88 High High
cytokine 5 32.80 Quite Low
metalloproteinase 1 16.12 Low Low
Bioavailability 1 7.32 Low Low
imagery 24 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
positron emission tomography 7 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 97 96.08 Very High Very High Very High
Organ Transplantation 6 87.36 High High
Hematological Disease 2 87.16 High High
Targeted Disruption 1 84.44 Quite High
Metastasis 7 80.56 Quite High
Wound Healing 1 80.48 Quite High
Disease 5 68.72 Quite High
Vascular Malformations 1 66.56 Quite High
Lymphatic Metastasis 1 60.72 Quite High
Hypoxia 3 27.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus we speculate that loss of NP2 promotes allograft survival at least in part by inhibiting dendritic cell trafficking through VEGFR-3-mediated signaling.
VEGFR-3-mediated Binding (trafficking) of in dendritic cell
1) Confidence 0.26 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2994732 Disease Relevance 0.49 Pain Relevance 0
VEGFR3 binds VEGF-C and -D and is directly involved in formation of the lymphatic vasculature physiologic and tumor development [27, 28].
VEGFR3 Binding (binds) of in vasculature associated with cancer
2) Confidence 0.08 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2902148 Disease Relevance 0.49 Pain Relevance 0.05

General Comments

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