INT32101

Context Info Confidence 0.26 First Reported 1989 Last Reported 2008 Negated 1 Speculated 0 Reported most in Abstract Documents 3 Total Number 3 Disease Relevance 0.89 Pain Relevance 1.31

plasma membrane (Mip) transmembrane transport (Mip)

Anatomy Link Frequency respiratory 1 T cell 1 Mip (Rattus norvegicus)

Pain Link Frequency Relevance Heat anesthesia 10 100.00 Inflammation 5 99.80 Pain 5 99.68 chemokine 6 97.84 Neuritis 2 95.08 Demyelination 1 25.00 Analgesic 1 5.00 ischemia 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 5 99.80 Immunization 2 95.20 Experimental Autoimmune Neuritis 2 95.08 Disease 4 93.52 Infection 1 59.60 Pneumonia 6 57.08 Pulmonary Disease 5 52.28 Cough 15 16.00 Respiratory Sounds 6 5.00 Pressure And Volume Under Development 5 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Interferon-gamma-inducible protein (IP)-10, monocyte chemotactic protein (MCP)-1, macrophage inflammatory protein (MIP)-1alpha, the regulated upon activation normal T cell expressed and secreted chemokine (RANTES), and lymphotactin were analyzed on days 0 (pre-immunization), 7 (preclinical stage), 10 (disease onset), 13 (clinical progression), 17 (disease peak), as well as on days 20, 24, and 34 post-immunization (p.i.)

Regulation (regulated) of MIP in T cell associated with chemokine, inflammation, immunization and disease

1) Confidence 0.26 Published 1999 Journal J. Neuroimmunol. Section Abstract Doc Link 10408979 Disease Relevance 0.73 Pain Relevance 0.44

In the first experiment, 8 subjects were tested for the effect of hypnotic anesthesia on sensory detection and MIP at non-painful stimulus levels (mean = 42.1 microA) and painful levels (mean = 86.5 microA).

Regulation (effect) of MIP associated with pain and anesthesia

2) Confidence 0.23 Published 1989 Journal Brain Res. Section Abstract Doc Link 2924158 Disease Relevance 0 Pain Relevance 0.88

P0.1/MIP is an index of balance between respiratory reserve and demand and reflects neuromuscular drive for breathing and it is unaffected by respiratory compliance or resistance.

Neg (unaffected) Regulation (unaffected) of MIP in respiratory

3) Confidence 0.06 Published 2008 Journal Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine Section Body Doc Link PMC2760915 Disease Relevance 0.17 Pain Relevance 0

General Comments

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