INT321996

Context Info Confidence 0.45 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

extracellular region (GABBR1) plasma membrane (GABBR1) transcription factor binding (GABBR1) cytoplasm (GABBR1) signal transducer activity (GABBR1)

GABBR1 (Homo sapiens)

Pain Link Frequency Relevance Heat Action potential 1 15.40 Glutamate receptor 1 5.00 TRP channel 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Pain 1 5.00 Nociception 1 5.00 Loss Of Sense Of Smell 1 5.00 Ganglion Cysts 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In heterodimeric GABAB receptors, GABABR1 binds the ligand while GABABR2 couples to the G protein and is required for targeting GABABR1 to the membrane (Brauner-Osborne et al., 2007).

Positive_regulation (required) of Regulation (targeting) of GABABR1

1) Confidence 0.45 Published 2010 Journal Frontiers in Cellular Neuroscience Section Body Doc Link PMC2906217 Disease Relevance 0 Pain Relevance 0

General Comments

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