INT322504

Context Info Confidence 0.06 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.69 Pain Relevance 0

peptidase activity (Ctsb) mitochondrion (Ctsb) extracellular space (Ctsb) extracellular region (Ctsb) lysosome (Ctsb) cytoplasm (Ctsb)

Ctsb (Mus musculus)

Pain Link Frequency Relevance Heat cINOD 1 5.00

Disease Link Frequency Relevance Heat Cancer 35 99.52 Glioma 26 50.00 Colon Cancer 2 28.72 Apoptosis 9 11.60 Hyperplasia 2 5.00 Metastasis 2 5.00 Adhesions 2 5.00 Retinoblastoma 1 5.00 Lung Cancer 1 5.00 Skin Cancer 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Immunohistochemical analysis of the tumor sections from control mice for cathepsin B and uPAR showed increased expression levels localized to the tumor region while the pCU-treated tumor sections revealed very little or no expression of the cathepsin B and uPAR.

Neg (little) Regulation (little) of Neg (no) Gene_expression (expression) of cathepsin B associated with cancer

1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908539 Disease Relevance 0.69 Pain Relevance 0

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