INT323173

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (THRA, Akt1) nucleus (THRA, Akt1) nucleoplasm (THRA)
transport (Akt1) aging (Akt1) enzyme binding (Akt1)
THRA (Homo sapiens)
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 38 99.92 Very High Very High Very High
Calcium channel 14 89.32 High High
Kinase C 12 55.96 Quite High
Hippocampus 2 50.24 Quite High
tetrodotoxin 8 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
GABAergic 6 5.00 Very Low Very Low Very Low
Serotonin 4 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hot Flashes 10 5.00 Very Low Very Low Very Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Breast Cancer 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Reprotox - General 3 2 5.00 Very Low Very Low Very Low
Endometriosis (extended) 2 5.00 Very Low Very Low Very Low
Uterine Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ERB-041, DPN and MF101 increased the phosphorylation of AKT (Figure 10A), ERK1/2 (Figure 10B), and CREB (Figure 10C) signaling similar to E2, whereas PPT was ineffective.
ERB-041 Positive_regulation (increased) of Phosphorylation (phosphorylation) of AKT
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910705 Disease Relevance 0 Pain Relevance 0.22

General Comments

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