INT323251

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Isl1, Uchl1) nucleus (Isl1, Uchl1) endoplasmic reticulum (Uchl1)
DNA binding (Isl1) ligase activity (Uchl1) response to stress (Uchl1)
Anatomy Link Frequency
T cells 1
Isl1 (Mus musculus)
Uchl1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 19 5.00 Very Low Very Low Very Low
tolerance 12 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
abatacept 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 1 100.00 Very High Very High Very High
Autoimmune Disease 5 93.96 High High
Diabetes Mellitus 48 91.76 High High
Disease 19 71.68 Quite High
Immunization 40 50.00 Quite Low
Prediabetic State 1 50.00 Quite Low
Disease Progression 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Lymphopenia 1 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In humans and mice, islet autoantibody specificities and epitopes for CD4+ and CD8+ T cells recognising insulin, GAD, islet tyrosine phosphatase IA-2 and islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) have been identified [1–4], but it is unclear which of these autoantigens are crucial for diabetes development.
islet Binding (recognising) of GAD in T cells associated with diabetes mellitus and generalized anxiety disorder
1) Confidence 0.00 Published 2010 Journal Diabetologia Section Body Doc Link PMC2910887 Disease Relevance 0.60 Pain Relevance 0

General Comments

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