INT323396

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.77
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (VRK1) nucleolus (VRK1) cytoskeleton (VRK1)
nucleus (VRK1) cell cycle (VRK1) cell division (VRK1)
VRK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 96.50 Very High Very High Very High
Central nervous system 2 74.44 Quite High
peripheral neuropathy 4 5.00 Very Low Very Low Very Low
induced neuropathy 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malaria 2 97.24 Very High Very High Very High
Hepatitis 2 96.72 Very High Very High Very High
Drug Dependence 2 96.50 Very High Very High Very High
Drug Induced Neurotoxicity 12 82.24 Quite High
Congenital Anomalies 4 81.52 Quite High
Freckles 10 66.40 Quite High
Hepatotoxicity 16 53.20 Quite High
Acute Promyelocytic Leukemia 8 41.28 Quite Low
Nicotine Addiction 2 13.28 Low Low
Disease 4 7.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduced levels of arsenic concentration in water are expected to increase the PChE activity to its normal level and decrease the risk of arsenic-induced pathogenesis.


Positive_regulation (increase) of PChE
1) Confidence 0.12 Published 2010 Journal Environ Health Section Body Doc Link PMC2911418 Disease Relevance 0.36 Pain Relevance 0.04
The individuals, who had previous and recent histories of drug addiction, hepatitis, hepatoxic drugs, malaria, and kalazar, and farmers exposed to any kind of agricultural/home insecticides within last one month, were also excluded as these could influence PChE activity.
Positive_regulation (influence) of PChE associated with malaria, drug dependence, addiction and hepatitis
2) Confidence 0.11 Published 2010 Journal Environ Health Section Body Doc Link PMC2911418 Disease Relevance 0.41 Pain Relevance 0.05

General Comments

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