INT324690

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.23
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Traf6, Ticam1) signal transduction (Traf6, Ticam1) protein complex assembly (Traf6)
protein complex (Traf6) ligase activity (Traf6) cytoplasm (Traf6)
Anatomy Link Frequency
nucleus 1
Traf6 (Mus musculus)
Ticam1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 23 97.12 Very High Very High Very High
chemokine 3 96.08 Very High Very High Very High
agonist 16 75.20 Quite High
Inflammation 23 70.32 Quite High
Inflammatory response 7 49.52 Quite Low
Central nervous system 21 5.00 Very Low Very Low Very Low
rheumatoid arthritis 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
Substantia nigra 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 30 70.32 Quite High
Necrosis 3 53.80 Quite High
Cancer 6 53.44 Quite High
Apoptosis 10 53.12 Quite High
Disease 71 50.00 Quite Low
Shock 2 34.12 Quite Low
Systemic Lupus Erythematosus 61 14.64 Low Low
Autoimmune Disease 24 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 17 5.00 Very Low Very Low Very Low
Prion Diseases 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B by the interaction of TRIF with TRAF6 or RIP1, which allow the transcription factor to migrate to the nucleus to induce target gene transcription [24, 28].
TRAF6 Binding (interaction) of TRIF in nucleus
1) Confidence 0.07 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2945668 Disease Relevance 0.18 Pain Relevance 0.11
Recent evidence indicates that TRIF associates with TRAF6 and induces NF-?
TRAF6 Binding (associates) of TRIF
2) Confidence 0.03 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913815 Disease Relevance 0.05 Pain Relevance 0.22

General Comments

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