INT325223

Context Info Confidence 0.38 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.58 Pain Relevance 0.11

signal transduction (Hrh4) extracellular space (Il13) extracellular region (Il13) plasma membrane (Hrh4) signal transducer activity (Hrh4) cytoplasm (Il13)

Anatomy Link Frequency lung 1 Il13 (Mus musculus) Hrh4 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 37 99.72 cytokine 30 69.88 antagonist 40 51.12 chemokine 5 5.00 Serotonin 2 5.00 anesthesia 1 5.00 Antihistamine 1 5.00

Disease Link Frequency Relevance Heat Asthma 43 99.84 Pneumonia 4 99.72 Fibrosis 1 94.00 Hyperplasia 13 61.24 INFLAMMATION 33 50.00 Airway Obstruction 1 41.68 Hypersensitivity 11 18.08 Disease 2 9.20 Rhinitis 3 5.00 Airway Remodeling 2 5.00

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Event

Anatomy

Negation

Speculation

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Disease term

We therefore utilized a previously reported acute model of ovalbumin induced lung inflammation to study the effects of H4R antagonism and IL-13 on AHR [6].

IL-13 Regulation (effects) of H4R in lung associated with asthma, inflammation and pneumonia

1) Confidence 0.38 Published 2010 Journal Respir Res Section Body Doc Link PMC2914735 Disease Relevance 0.58 Pain Relevance 0.11

General Comments

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