INT325506

Context Info Confidence 0.05 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.28 Pain Relevance 0.17

cell differentiation (Ctnnb1) enzyme binding (Ctnnb1) DNA binding (Ctnnb1) protein complex (Ctnnb1) cytoplasm (Ctnnb1) cell proliferation (Ctnnb1)

Ctnnb1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat antidepressant 2 92.32 Hippocampus 22 61.68 dexamethasone 7 51.16 cINOD 1 21.68 Inflammation 17 10.08 cytokine 8 5.00 Central nervous system 6 5.00 Inflammatory response 3 5.00 chemokine 3 5.00 metalloproteinase 2 5.00

Disease Link Frequency Relevance Heat Pneumococcal Meningitis 21 83.04 Neurodegenerative Disease 10 76.28 Infection 60 62.72 Disease 33 56.44 Apoptosis 20 42.04 Death 4 36.12 Bacterial Meningitis 28 34.68 INFLAMMATION 21 21.28 Acute Disease 5 5.00 Injury 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the same line of evidence it was demonstrated that the chronic administration of the dual reuptake inhibitor venlafaxine induces the nuclear translocation of beta-catenin most likely by an inhibition of GSK3?

Spec (likely) Positive_regulation (induces) of Localization (translocation) of beta-catenin

1) Confidence 0.05 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC2915993 Disease Relevance 0.28 Pain Relevance 0.17

General Comments

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