INT326096

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.57 Pain Relevance 0.23

cytosol (RPL18A) structural constituent of ribosome (RPL18A) ribosome (RPL18A) RNA binding (RPL18A) translation (RPL18A)

RPL18A (Homo sapiens)

Pain Link Frequency Relevance Heat Cannabinoid 57 88.00 antagonist 2 61.04 metalloproteinase 5 25.60 Cannabinoid receptor 7 5.00 agonist 7 5.00 Endocannabinoid 2 5.00 Central nervous system 1 5.00 Inflammation 1 5.00 Pain 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Cancer 93 99.56 Breast Cancer 34 92.20 Metastasis 20 11.00 Adenocarcinoma 1 8.88 Advanced Or Metastatic Breast Cancer 4 5.00 Apoptosis 4 5.00 Heart Rate Under Development 2 5.00 Ductal Carcinoma 2 5.00 Infection 2 5.00 Recurrence 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We observed a decrease in Akt activation in THC-treated MMTV-neu tumors (Fig. 5B) as well as diminished levels of phosphorylated S6 ribosomal protein [a read-out for activation of the Akt/mammalian target of rapamycin (mTOR) pathway [12]] (Fig. 5C).

Negative_regulation (diminished) of ribosomal protein associated with cancer

1) Confidence 0.01 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2917429 Disease Relevance 0.57 Pain Relevance 0.23

General Comments

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