INT326142

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.47
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TYMS) mitochondrion (TYMS) small molecule metabolic process (TYMS)
aging (TYMS) cytoplasm (TYMS) cytosol (TYMS)
Anatomy Link Frequency
lymph node 4
TYMS (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 8 30.12 Quite Low
COX2 6 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 86 98.94 Very High Very High Very High
Colon Cancer 124 98.84 Very High Very High Very High
Metastasis 16 97.66 Very High Very High Very High
Apoptosis 8 70.36 Quite High
Stress 2 62.80 Quite High
Recurrence 20 40.32 Quite Low
Breast Cancer 8 37.76 Quite Low
Repression 6 23.68 Low Low
Mouth Cancer 4 5.00 Very Low Very Low Very Low
Lung Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sharma et al reported that 5-FU resistance was stronger in patients with overexpression of either TYMS mRNA or protein.35 Although the relation between TYMS with lymph node metastasis is not clear, we are now analyzing its relationship with cancer resistance, as we observed the copy number gain and overexpression of TYMS more frequently in advanced CRC cases.
Positive_regulation (overexpression) of Gene_expression (overexpression) of TYMS mRNA in lymph node associated with cancer, colon cancer and metastasis
1) Confidence 0.16 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 1.25 Pain Relevance 0
Sharma et al reported that 5-FU resistance was stronger in patients with overexpression of either TYMS mRNA or protein.35 Although the relation between TYMS with lymph node metastasis is not clear, we are now analyzing its relationship with cancer resistance, as we observed the copy number gain and overexpression of TYMS more frequently in advanced CRC cases.
Positive_regulation (overexpression) of Gene_expression (overexpression) of TYMS in lymph node associated with cancer, colon cancer and metastasis
2) Confidence 0.14 Published 2010 Journal Cancer Informatics Section Body Doc Link PMC2918356 Disease Relevance 1.23 Pain Relevance 0

General Comments

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